Transgenic 6F tomatoes act on the small intestine to prevent systemic inflammation and dyslipidemia caused by Western diet and intestinally derived lysophosphatidic acid[S]

Transgenic 6F tomatoes act on the small intestine to prevent systemic inflammation and dyslipidemia caused by Western diet and intestinally derived lysophosphatidic acid[S]

We recently reported that levels of unsaturated lysophosphatidic acid (LPA) in the small intestine significantly correlated with the extent of aortic atherosclerosis in LDL receptor-null (LDLR−/−) mice fed a Western diet (WD). Here we demonstrate that WD increases unsaturated (but not saturated) LPA...

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Bibliographic Details
Main Authors: Mohamad Navab, Greg Hough, Georgette M. Buga, Feng Su, Alan C. Wagner, David Meriwether, Arnab Chattopadhyay, Feng Gao, Victor Grijalva, Janet S. Danciger, Brian J. Van Lenten, Elin Org, Aldons J. Lusis, Calvin Pan, G.M. Anantharamaiah, Robin Farias-Eisner, Susan S. Smyth, Srinivasa T. Reddy, Alan M. Fogelman
Format: Article
Language:English
Published: Elsevier 2013-12-01
Series:Journal of Lipid Research
Subjects:
6F peptide
apolipoprotein A-I mimetic peptides
atherosclerosis
lysophosphatidic acid
genetically engineered tomato plants
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520356923

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http://www.sciencedirect.com/science/article/pii/S0022227520356923

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