Genome-wide analysis of KAP1, the 7SK snRNP complex, and RNA polymerase II

The transition of RNA polymerase II (Pol II) from transcription initiation into productive elongation in eukaryotic cells is regulated by the P-TEFb kinase, which phosphorylates the C-terminal domain of paused Pol II at promoter-proximal regions. Our recent study found that P-TEFb (in an inhibited s...

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Bibliographic Details
Main Authors: Ryan P. McNamara, Carlos Guzman, Jonathan E. Reeder, Iván D'Orso
Format: Article
Language:English
Published: Elsevier 2016-03-01
Series:Genomics Data
Online Access:http://www.sciencedirect.com/science/article/pii/S2213596016300198