Optimization of fluorophores for chemical tagging and immunohistochemistry of Drosophila neurons.

The use of genetically encoded 'self-labeling tags' with chemical fluorophore ligands enables rapid labeling of specific cells in neural tissue. To improve the chemical tagging of neurons, we synthesized and evaluated new fluorophore ligands based on Cy, Janelia Fluor, Alexa Fluor, and ATT...

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Bibliographic Details
Main Authors: Geoffrey W Meissner, Jonathan B Grimm, Rebecca M Johnston, Ben Sutcliffe, Julian Ng, Gregory S X E Jefferis, Sebastian Cachero, Luke D Lavis, Oz Malkesman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6093644?pdf=render