Smoking modifies the associated increased risk of future cardiovascular disease by genetic variation on chromosome 9p21.

<h4>Aims</h4>Genetic predisposition for cardiovascular disease (CVD) is likely to be modified by environmental exposures. We tested if the associated risk of CVD and CVD-mortality by the single nucleotide polymorphism rs4977574 on chromosome 9p21 is modified by life-style factors.<h4&...

Full description

Bibliographic Details
Main Authors: Viktor Hamrefors, Bo Hedblad, George Hindy, J Gustav Smith, Peter Almgren, Gunnar Engström, Marketa Sjögren, Klas Gränsbo, Marju Orho-Melander, Olle Melander
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24465769/?tool=EBI