Nonenzymatic oxidative cleavage of peptide bonds in apoprotein B-100.
Incubation of low density lipoprotein (LDL) with endothelial cells converts it to a form that is avidly degraded by macrophages via the acetyl LDL receptor. This modification has previously been shown to be accompanied by extensive breakdown of the major LDL protein (apoB-100) to smaller peptides. A...
Main Authors: | L G Fong, S Parthasarathy, J L Witztum, D Steinberg |
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Format: | Article |
Language: | English |
Published: |
Elsevier
1987-12-01
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Series: | Journal of Lipid Research |
Online Access: | http://www.sciencedirect.com/science/article/pii/S002222752038576X |
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