Mimicking and surpassing the xenograft model with cancer-on-chip technology

Organs-on-chips are in vitro models in which human tissues are cultured in microfluidic compartments with a controlled, dynamic micro-environment. Specific organs-on-chips are being developed to mimic human tumors, but the validation of such ‘cancer-on-chip’ models for use in drug development is ham...

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Bibliographic Details
Main Authors: Job Komen, Sanne M. van Neerven, Albert van den Berg, Louis Vermeulen, Andries D. van der Meer
Format: Article
Language:English
Published: Elsevier 2021-04-01
Series:EBioMedicine
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396421000967