Progression of Epididymal Maldevelopment Into Hamartoma-like Neoplasia in VHL Disease

Progression of Epididymal Maldevelopment Into Hamartoma-like Neoplasia in VHL Disease

Inactivation of the von Hippel-Lindau (VHL) gene and activation of the hypoxia-inducible factor (HIF) in susceptible cells precedes formation of tumorlets and frank tumor in the epididymis of male VHL patients. We performed detailed histologic and molecular pathologic analysis of tumor-free epididy...

Full description

Bibliographic Details
Main Authors: Gautam U. Mehta, Sharon B. Shively, Heng Duong, Maxine G.B. Tran, Travis J. Moncrief, Jonathan H. Smith, Jie Li, Nancy A. Edwards, Russell R. Lonser, Zhengping Zhuang, Marsha J. Merrill, Mark Raffeld, Patrick H. Maxwell, Edward H. Oldfield, Alexander O. Vortmeyer
Format: Article
Language:English
Published: Elsevier 2008-10-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558608801054

Internet

http://www.sciencedirect.com/science/article/pii/S1476558608801054

Similar Items