Predictable Phenotypes of Antibiotic Resistance Mutations

Antibiotic-resistant bacteria represent a major threat to our ability to treat bacterial infections. Two factors that determine the evolutionary success of antibiotic resistance mutations are their impact on resistance level and the fitness cost. Recent studies suggest that resistance mutations comm...

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Bibliographic Details
Main Authors: M. Knopp, D. I. Andersson
Format: Article
Language:English
Published: American Society for Microbiology 2018-05-01
Series:mBio
Subjects:
Online Access:https://doi.org/10.1128/mBio.00770-18