Mimotopes for alloreactive and conventional T cells in a peptide-MHC display library.

The use of peptide libraries for the identification and characterization of T cell antigen peptide epitopes and mimotopes has been hampered by the need to form complexes between the peptides and an appropriate MHC molecule in order to construct a complete T cell ligand. We have developed a baculovir...

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Bibliographic Details
Main Authors: Frances Crawford, Eric Huseby, Janice White, Philippa Marrack, John W Kappler
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2004-04-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC387264?pdf=render