Epileptiform activity in mouse hippocampal slices induced by moderate changes in extracellular Mg2+, Ca2+, and K+
Abstract Background Rodent brain slices—particularly hippocampal slices—are widely used in experimental investigations of epileptiform activity. Oxygenated artificial cerebrospinal fluid (ACSF) is used to maintain slices in vitro. Physiological or standard ACSF containing 3–3.5 mM K+, 1–2 mM Mg2+, a...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2021-07-01
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Series: | BMC Neuroscience |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12868-021-00650-3 |