Epileptiform activity in mouse hippocampal slices induced by moderate changes in extracellular Mg2+, Ca2+, and K+

Abstract Background Rodent brain slices—particularly hippocampal slices—are widely used in experimental investigations of epileptiform activity. Oxygenated artificial cerebrospinal fluid (ACSF) is used to maintain slices in vitro. Physiological or standard ACSF containing 3–3.5 mM K+, 1–2 mM Mg2+, a...

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Bibliographic Details
Main Authors: Haiyu Liu, Sai Zhang, Liang Zhang
Format: Article
Language:English
Published: BMC 2021-07-01
Series:BMC Neuroscience
Subjects:
Online Access:https://doi.org/10.1186/s12868-021-00650-3