Cellular aspect ratio and cell division mechanics underlie the patterning of cell progeny in diverse mammalian epithelia

Cellular aspect ratio and cell division mechanics underlie the patterning of cell progeny in diverse mammalian epithelia

Cell division is essential to expand, shape, and replenish epithelia. In the adult small intestine, cells from a common progenitor intermix with other lineages, whereas cell progeny in many other epithelia form contiguous patches. The mechanisms that generate these distinct patterns of progeny are p...

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Bibliographic Details
Main Authors: Kara L McKinley, Nico Stuurman, Loic A Royer, Christoph Schartner, David Castillo-Azofeifa, Markus Delling, Ophir D Klein, Ronald D Vale
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2018-06-01
Series:eLife
Subjects:
organoid
light sheet microscopy
epithelium
mitosis
intestine
stem cell
Online Access:https://elifesciences.org/articles/36739

Internet

https://elifesciences.org/articles/36739

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