Co‐occurrence of germline pathogenic variants for different hereditary cancer syndromes in patients with Lynch syndrome

Abstract Background Lynch syndrome (LS) is a hereditary condition characterized by a high risk of colorectal cancer, endometrial cancer, and other neoplasia associated with germline alterations in DNA mismatch repair genes. The classical genetic diagnostic strategy for LS consists of the Sanger sequ...

Full description

Bibliographic Details
Main Authors: Rosario Ferrer‐Avargues, María Isabel Castillejo, Estela Dámaso, Virginia Díez‐Obrero, Noemí Garrigos, Tatiana Molina, Alan Codoñer‐Alejos, Ángel Segura, Ana Beatriz Sánchez‐Heras, Adela Castillejo, José Luis Soto
Format: Article
Language:English
Published: Wiley 2021-03-01
Series:Cancer Communications
Subjects:
Online Access:https://doi.org/10.1002/cac2.12134