Co‐occurrence of germline pathogenic variants for different hereditary cancer syndromes in patients with Lynch syndrome
Abstract Background Lynch syndrome (LS) is a hereditary condition characterized by a high risk of colorectal cancer, endometrial cancer, and other neoplasia associated with germline alterations in DNA mismatch repair genes. The classical genetic diagnostic strategy for LS consists of the Sanger sequ...
Main Authors: | , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Wiley
2021-03-01
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Series: | Cancer Communications |
Subjects: | |
Online Access: | https://doi.org/10.1002/cac2.12134 |