Structural and functional basis for RNA cleavage by Ire1

<p>Abstract</p> <p>Background</p> <p>The unfolded protein response (UPR) controls the protein folding capacity of the endoplasmic reticulum (ER). Central to this signaling pathway is the ER-resident bifunctional transmembrane kinase/endoribonuclease Ire1. The endoribonu...

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Bibliographic Details
Main Authors: Stroud Robert M, Finer-Moore Janet, Egea Pascal F, Korostelev Andrei A, Korennykh Alexei V, Zhang Chao, Shokat Kevan M, Walter Peter
Format: Article
Language:English
Published: BMC 2011-07-01
Series:BMC Biology
Online Access:http://www.biomedcentral.com/1741-7007/9/47