Involvement of ClC-3 chloride/proton exchangers in controlling glutamatergic synaptic strength in cultured hippocampal neurons

Involvement of ClC-3 chloride/proton exchangers in controlling glutamatergic synaptic strength in cultured hippocampal neurons

ClC-3 is a member of the CLC family of anion channels and transporters that localizes to early and late endosomes as well as to synaptic vesicles. Its genetic disruption in mouse models results in pronounced hippocampal and retinal neurodegeneration, suggesting that ClC-3 might be important for norm...

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Bibliographic Details
Main Authors: Raul Enrique Guzman, Alexi eAlekov, Mikhail eFilippov, Jan eHegermannd, Christoph eFahlke
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-05-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Neurons
EPSC
mEPSC
ClC-3
-DGG
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2014.00143/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fncel.2014.00143/full

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