Individual Assessment of Brain Tissue Changes in MS and the Effect of Focal Lesions on Short-Term Focal Atrophy Development in MS: A Voxel-Guided Morphometry Study

Individual Assessment of Brain Tissue Changes in MS and the Effect of Focal Lesions on Short-Term Focal Atrophy Development in MS: A Voxel-Guided Morphometry Study

We performed voxel-guided morphometry (VGM) investigating the mechanisms of brain atrophy in multiple sclerosis (MS) related to focal lesions. VGM maps detect regional brain changes when comparing 2 time points on high resolution T1-weighted (T1w) magnetic resonace imaging (MRI). Two T1w MR datasets...

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Bibliographic Details
Main Authors: Jan Fox, Matthias Kraemer, Thorsten Schormann, Andreas Dabringhaus, Jochen Hirsch, Philipp Eisele, Kristina Szabo, Christel Weiss, Michael Amann, Katrin Weier, Yvonne Naegelin, Ludwig Kappos, Achim Gass
Format: Article
Language:English
Published: MDPI AG 2016-04-01
Series:International Journal of Molecular Sciences
Subjects:
regional brain atrophy
multiple sclerosis
voxel
lesion
corpus callosum
lateral geniculate nucleus
shrinking
retrograde degeneration
Wallerian degeneration
Online Access:http://www.mdpi.com/1422-0067/17/4/489

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http://www.mdpi.com/1422-0067/17/4/489

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