<i>FMR1</i> and AKT/mTOR Signaling in Human Granulosa Cells: Functional Interaction and Impact on Ovarian Response

<i>FMR1</i> and AKT/mTOR Signaling in Human Granulosa Cells: Functional Interaction and Impact on Ovarian Response

We aimed to determine whether a functional link with impact on female ovarian reserve exists between <i>FMR1</i> expression and expression ratios of AKT/mTOR signaling genes in human granulosa cells in vivo, as suggested from prior in vitro data. Three hundred and nine women, who were cl...

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Bibliographic Details
Main Authors: Julia Rehnitz, Edison Capp, Birgitta Messmer, Xuan Phuoc Nguyen, Ariane Germeyer, Alexander Freis, Jens Erik Dietrich, Karin Hinderhofer, Thomas Strowitzki, Peter H. Vogt
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Journal of Clinical Medicine
Subjects:
<i>FMR1</i>
granulosa cells
<i>AKT1</i>
<i>FOXO3</i>
<i>FOXO1</i>
<i>mTOR</i>
Online Access:https://www.mdpi.com/2077-0383/10/17/3892

Internet

https://www.mdpi.com/2077-0383/10/17/3892

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