Synthesis, Antiproliferative and Antifungal Activities of 1,2,3-Triazole-Substituted Carnosic Acid and Carnosol Derivatives

Synthesis, Antiproliferative and Antifungal Activities of 1,2,3-Triazole-Substituted Carnosic Acid and Carnosol Derivatives

Abietane diterpenes exhibit an array of interesting biological activities, which have generated significant interest among the pharmacological community. Starting from the abietane diterpenes carnosic acid and carnosol, twenty four new triazole derivatives were synthesized using click chemistry. The...

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Bibliographic Details
Main Authors: Mariano Walter Pertino, Cristina Theoduloz, Estefania Butassi, Susana Zacchino, Guillermo Schmeda-Hirschmann
Format: Article
Language:English
Published: MDPI AG 2015-05-01
Series:Molecules
Subjects:
carnosic acid
carnosol
click chemistry
antiproliferative
antifungal
Online Access:http://www.mdpi.com/1420-3049/20/5/8666

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http://www.mdpi.com/1420-3049/20/5/8666

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