Detecting Early Biomechanical Effects of Zoledronic Acid on Femurs of Osteoporotic Female Rats

Aim. To investigate the biomechanical effects of zoledronic acid (ZA) on femurs of female osteoporotic rats after follow-up periods of 9 and 12 months. Methods. Eighty female Wistar rats were prospectively assessed. At 60 days of age, the animals were randomly divided into two groups: bilateral ooph...

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Bibliographic Details
Main Authors: Evandro Pereira Palacio, Sérgio Swain Müller, Trajano Sardenberg, Roberto Ryuiti Mizobuchi, José Antônio Galbiatti, Alcides Durigan, Aniello Savarese, Érika Veruska Paiva Ortolan
Format: Article
Language:English
Published: Hindawi Limited 2012-01-01
Series:Journal of Osteoporosis
Online Access:http://dx.doi.org/10.1155/2012/162806