Differential effects of allergen challenge on large and small airway reactivity in mice.

The relative contributions of large and small airways to hyperresponsiveness in asthma have yet to be fully assessed. This study used a mouse model of chronic allergic airways disease to induce inflammation and remodelling and determine whether in vivo hyperresponsiveness to methacholine is consiste...

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Bibliographic Details
Main Authors: Chantal Donovan, Simon G Royce, James Esposito, Jenny Tran, Zaridatul Aini Ibrahim, Mimi L K Tang, Simon Bailey, Jane E Bourke
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3765301?pdf=render