Implant for Augmentation of Cerebral Blood Flow Trial-1 (ImpACT-1). A single-arm feasibility study evaluating the safety and potential benefit of the Ischemic Stroke System for treatment of acute ischemic stroke.

BACKGROUND:The Ischemic Stroke System is a novel device designed to deliver stimulation to the sphenopalatine ganglion(SPG).The SPG sends parasympathetic innervations to the anterior cerebral circulation. In rat stroke models, SPG stimulation results in increased cerebral blood flow, reduced infarct...

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Main Authors: Dheeraj Khurana, Subhash Kaul, Dietmar Schneider, Attila Csanyi, Ilona Adam, Nasli R Ichaporia, Bernd Griewing, Laszlo Csiba, Attila Valikovics, Vinod Puri, Hans Christoph Diener, Stefan Schwab, Andreas Hetzel, Natan Bornstein, ImpACT-1 Study Group
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0217472