MicroRNA-146a regulates human foetal femur derived skeletal stem cell differentiation by down-regulating SMAD2 and SMAD3.

MicroRNA-146a regulates human foetal femur derived skeletal stem cell differentiation by down-regulating SMAD2 and SMAD3.

MicroRNAs (miRs) play a pivotal role in a variety of biological processes including stem cell differentiation and function. Human foetal femur derived skeletal stem cells (SSCs) display enhanced proliferation and multipotential capacity indicating excellent potential as candidates for tissue enginee...

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Bibliographic Details
Main Authors: Kelvin S C Cheung, Nunzia Sposito, Patrick S Stumpf, David I Wilson, Tilman Sanchez-Elsner, Richard O C Oreffo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4043645?pdf=render

Internet

http://europepmc.org/articles/PMC4043645?pdf=render

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