Comprehensive Study of Germline Mutations and Double-Hit Events in Esophageal Squamous Cell Cancer

Comprehensive Study of Germline Mutations and Double-Hit Events in Esophageal Squamous Cell Cancer

Esophageal squamous cell cancer (ESCC) is the eighth most common cancer around the world. Several reports have focused on somatic mutations and common germline mutations in ESCC. However, the contributions of pathogenic germline alterations in cancer susceptibility genes (CSGs), highly frequently mu...

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Bibliographic Details
Main Authors: Bing Zeng, Peide Huang, Peina Du, Xiaohui Sun, Xuanlin Huang, Xiaodong Fang, Lin Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Oncology
Subjects:
esophageal squamous cell cancer
cancer susceptibility gene
double-hit
germline mutation
pathogenicity
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.637431/full

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https://www.frontiersin.org/articles/10.3389/fonc.2021.637431/full

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