Curcumin Veto the Effects of Osteopontin (OPN) Specific Inhibitor on Leukemic Stem Cell Colony Forming Potential via Promotion of OPN Overexpression

Curcumin Veto the Effects of Osteopontin (OPN) Specific Inhibitor on Leukemic Stem Cell Colony Forming Potential via Promotion of OPN Overexpression

Background: Acute myeloid leukemia (AML) is an immunophenotypically heterogeneous malignant disease, in which CD34 positivity is associated with poor prognosis. Osteopontin (OPN) plays different roles in physiologic and pathologic conditions like: survival, metastasis and cell protection from cytoto...

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Bibliographic Details
Main Authors: Saeed Mohammadi, Seyed H Ghaffari, Mojgan Shaiegan, Mahin Nikogoftar Zarif, Mohsen Nikbakht, Kamran Alimoghaddam, Ardeshir Ghavamzadeh
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2016-06-01
Series:International Journal of Hematology-Oncology and Stem Cell Research
Subjects:
Curcumin
Osteopontin
Leukemic stem cell
Colony forming potential
SiRNA
Online Access:https://ijhoscr.tums.ac.ir/index.php/ijhoscr/article/view/498

Internet

https://ijhoscr.tums.ac.ir/index.php/ijhoscr/article/view/498

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