Microglia Increase Inflammatory Responses in iPSC-Derived Human BrainSpheres

Microglia Increase Inflammatory Responses in iPSC-Derived Human BrainSpheres

Human induced pluripotent stem cells (iPSCs), together with 21st century cell culture methods, have the potential to better model human physiology with applications in toxicology, disease modeling, and the study of host-pathogen interactions. Several models of the human brain have been developed rec...

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Bibliographic Details
Main Authors: Celina Monteiro Abreu, Lucio Gama, Susanne Krasemann, Megan Chesnut, Shelly Odwin-Dacosta, Helena T. Hogberg, Thomas Hartung, David Pamies
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-12-01
Series:Frontiers in Microbiology
Subjects:
zika virus
organoids
microglial cells
in vitro culture
BrainSpheres
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2018.02766/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2018.02766/full

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