Evolution of substrate specificity in the Nucleobase-Ascorbate Transporter (NAT) protein family

L-ascorbic acid (vitamin C) is an essential metabolite in animals and plants due to its role as an enzyme co-factor and antioxidant activity. In most eukaryotic organisms, L-ascorbate is biosynthesized enzymatically, but in several major groups, including the primate suborder Haplorhini, this abilit...

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Bibliographic Details
Main Authors: Anezia Kourkoulou, Alexandros A. Pittis, George Diallinas
Format: Article
Language:English
Published: Shared Science Publishers OG 2018-03-01
Series:Microbial Cell
Subjects:
Online Access:http://microbialcell.com/researcharticles/evolution-of-substrate-specificity-in-the-nucleobase-ascorbate-transporter-nat-protein-family/