Preservation of cellular nano-architecture by the process of chemical fixation for nanopathology.

Transformation in chromatin organization is one of the most universal markers of carcinogenesis. Microscale chromatin alterations have been a staple of histopathological diagnosis of neoplasia, and nanoscale alterations have emerged as a promising marker for cancer prognostication and the detection...

Full description

Bibliographic Details
Main Authors: Xiang Zhou, Scott Gladstein, Luay M Almassalha, Yue Li, Adam Eshein, Lusik Cherkezyan, Parvathi Viswanathan, Hariharan Subramanian, Igal Szleifer, Vadim Backman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0219006