Down-Regulation of Ca2+-Activated K+ Channel KCa1.1 in Human Breast Cancer MDA-MB-453 Cells Treated with Vitamin D Receptor Agonists

Down-Regulation of Ca2+-Activated K+ Channel KCa1.1 in Human Breast Cancer MDA-MB-453 Cells Treated with Vitamin D Receptor Agonists

Vitamin D (VD) reduces the risk of breast cancer and improves disease prognoses. Potential VD analogs are being developed as therapeutic agents for breast cancer treatments. The large-conductance Ca2+-activated K+ channel KCa1.1 regulates intracellular Ca2+ signaling pathways and is associated with...

Full description

Bibliographic Details
Main Authors: Anowara Khatun, Mayu Fujimoto, Hiroaki Kito, Satomi Niwa, Takayoshi Suzuki, Susumu Ohya
Format: Article
Language:English
Published: MDPI AG 2016-12-01
Series:International Journal of Molecular Sciences
Subjects:
vitamin D receptor
breast cancer
KCa1.1
K+ channel
transcription
protein degradation
Online Access:http://www.mdpi.com/1422-0067/17/12/2083

Internet

http://www.mdpi.com/1422-0067/17/12/2083

Similar Items