A DNA origami-based aptamer nanoarray for potent and reversible anticoagulation in hemodialysis

A DNA origami-based aptamer nanoarray for potent and reversible anticoagulation in hemodialysis

Safe haemodialysis is essential for patients with acute kidney injury and renal failure. Here the authors present a DNA origami-based approach with high affinity and specificity to thrombin, inhibiting coagulation.

Bibliographic Details
Main Authors: Shuai Zhao, Run Tian, Jun Wu, Shaoli Liu, Yuanning Wang, Meng Wen, Yingxu Shang, Qing Liu, Yan Li, Ying Guo, Zhaoran Wang, Ting Wang, Yujing Zhao, Huiru Zhao, Hui Cao, Yu Su, Jiashu Sun, Qiao Jiang, Baoquan Ding
Format: Article
Language:English
Published: Nature Publishing Group 2021-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-20638-7

Internet

https://doi.org/10.1038/s41467-020-20638-7

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