Linkage disequilibrium pattern of the <it>ATM </it>gene in breast cancer patients and controls; association of SNPs and haplotypes to radio-sensitivity and post-lumpectomy local recurrence

<p>Abstract</p> <p>Background</p> <p>The ATM protein is activated as a result of ionizing radiation, and genetic variants of the <it>ATM </it>gene may therefore affect the level of radiation-induced damage. Individuals heterozygous for <it>ATM </it&...

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Bibliographic Details
Main Authors: Fosså Sophie D, Haffty Bruce G, Vu Phuong, Jansen Laila, Tefre Toril, Edvardsen Hege, Kristensen Vessela N, Børresen-Dale Anne-Lise
Format: Article
Language:English
Published: BMC 2007-07-01
Series:Radiation Oncology
Online Access:http://www.ro-journal.com/content/2/1/25