Response-adapted radiation therapy for newly diagnosed primary diffuse large B-cell lymphoma of the CNS treated with methotrexate-based systemic therapy

Background: For patients with primary diffuse large B-cell lymphoma of the central nervous system (PCNSL), whole-brain radiation therapy (WBRT) to doses of ≥45 Gy are often given after a partial response (PR) to methotrexate-based induction chemotherapy. We conducted an exploratory analysis to deter...

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Main Authors: Tommy Sheu, MD, Sarah A. Milgrom, MD, Therese Y. Andraos, MD, Jillian R. Gunther, MD, PhD, Linda Chi, MD, Loretta Nastoupil, MD, Nathan Fowler, MD, Yasuhiro Oki, MD, Michelle A. Fanale, MD, Luis E. Fayad, MD, Fredrick Hagemeister, MD, Sattva S. Neelapu, MD, L. Jeffrey Medeiros, MD, Chitra Hosing, MD, Yago Nieto, MD, PhD, Sairah Ahmed, MD, Amin M. Alousi, MD, Bouthaina Dabaja, MD, Chelsea C. Pinnix, MD, PhD
Format: Article
Language:English
Published: Elsevier 2018-10-01
Series:Advances in Radiation Oncology
Online Access:http://www.sciencedirect.com/science/article/pii/S2452109418301222