Orientation of Antigen Display on Self-Assembling Protein Nanoparticles Influences Immunogenicity

Orientation of Antigen Display on Self-Assembling Protein Nanoparticles Influences Immunogenicity

Self-assembling protein nanoparticles (SAPN) serve as a repetitive antigen delivery platform with high-density epitope display; however, antigen characteristics such as size and epitope presentation can influence the immunogenicity of the assembled particle and are aspects to consider for a rational...

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Bibliographic Details
Main Authors: Cosette G. Schneider, Justin A. Taylor, Michael Q. Sibilo, Kazutoyo Miura, Katherine L. Mallory, Christopher Mann, Christopher Karch, Zoltan Beck, Gary R. Matyas, Carole A. Long, Elke Bergmann-Leitner, Peter Burkhard, Evelina Angov
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Vaccines
Subjects:
self-assembling protein nanoparticles
PfCelTOS
PfMSP1<sub>19</sub>
vaccine
multi-stage
display
Online Access:https://www.mdpi.com/2076-393X/9/2/103

Internet

https://www.mdpi.com/2076-393X/9/2/103

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