Enhancement of antibiotic activity by efflux inhibitors against multidrug resistant Mycobacterium tuberculosis clinical isolates from Brazil

Enhancement of antibiotic activity by efflux inhibitors against multidrug resistant Mycobacterium tuberculosis clinical isolates from Brazil

Drug resistant tuberculosis continues to increase and new approaches for its treatment are necessary. The identification of M. tuberculosis clinical isolates presenting efflux as part of their resistant phenotype has a major impact in tuberculosis treatment. In this work, we used a checkerboard proc...

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Bibliographic Details
Main Authors: Tatiane eCoelho, Diana eMachado, Isabel eCouto, Raquel eMaschmann, Daniela eRamos, Andrea evon Groll, Maria Lucia Rossetti, Pedro Almeida Silva, Miguel eViveiros
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-04-01
Series:Frontiers in Microbiology
Subjects:
Drug Resistance
Fluorometry
Tuberculosis
checkerboard
tema
fractional inhibitory concentration
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2015.00330/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fmicb.2015.00330/full

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