Ceramide kinase is required for a normal eicosanoid response and the subsequent orderly migration of fibroblasts[S]

In these studies, the role of ceramide-1-phosphate (C1P) in the wound-healing process was investigated. Specifically, fibroblasts isolated from mice with the known anabolic enzyme for C1P, ceramide kinase (CERK), ablated (CERK−/− mice) and their wild-type littermates (CERK+/+) were subjected to in v...

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Bibliographic Details
Main Authors: Dayanjan S. Wijesinghe, Matthew Brentnall, Jennifer A. Mietla, L. Alexis Hoeferlin, Robert F. Diegelmann, Lawrence H. Boise, Charles E. Chalfant
Format: Article
Language:English
Published: Elsevier 2014-07-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520352378