Genetic variation of Plasmodium falciparum histidine-rich protein 2 and 3 in Assosa zone, Ethiopia: its impact on the performance of malaria rapid diagnostic tests

Genetic variation of Plasmodium falciparum histidine-rich protein 2 and 3 in Assosa zone, Ethiopia: its impact on the performance of malaria rapid diagnostic tests

Abstract Background Rapid diagnostic tests (RDT) are commonly used for the diagnosis of malaria caused by Plasmodium falciparum. However, false negative results of RDT caused by genetic variation of P. falciparum histidine-rich protein 2 and 3 genes (pfhrp2/3) threaten existing malaria case manageme...

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Bibliographic Details
Main Authors: Gezahegn Solomon Alemayehu, Alebachew Messele, Kayla Blackburn, Karen Lopez, Eugenia Lo, Daniel Janies, Lemu Golassa
Format: Article
Language:English
Published: BMC 2021-10-01
Series:Malaria Journal
Subjects:
RDT
Plasmodium falciparum
Genetic variation
PfHRP2
PfHRP3
Amino acid sequence
Online Access:https://doi.org/10.1186/s12936-021-03928-3

Internet

https://doi.org/10.1186/s12936-021-03928-3

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