VEGFR-1 Regulates EGF-R to Promote Proliferation in Colon Cancer Cells

The relationship between epidermal growth factor (EGF) and vascular endothelial growth factor (VEGF) pathways in tumor growth is well established. EGF induces VEGF production in cancer cells, and the paracrine VEGF activates vascular endothelial cells to promote tumor angiogenesis and thus supports...

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Bibliographic Details
Main Authors: Hikaru Nagano, Chisato Tomida, Naoko Yamagishi, Shigetada Teshima-Kondo
Format: Article
Language:English
Published: MDPI AG 2019-11-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/20/22/5608