Effect of Hydrophilic Polymers on Complexation Efficiency of Cyclodextrins in Enhancing Solubility and Release of Diflunisal

The effects of three hydrophilic polymers, namely, carboxymethyl cellulose sodium (CMC-Na), polyvinyl alcohol (PVA) and poloxamer-188 (PXM-188) on the solubility and dissolution of diflunisal (DIF) in complexation with β-cyclodextrin (βCD) or hydroxypropyl β-cyclodextrin (HPβCD), were investigated....

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Main Authors: Mehreen Bashir, Haroon Khalid Syed, Sajid Asghar, Muhammad Irfan, Waleed Hassan Almalki, Salah Ali Menshawi, Ikram Ullah Khan, Pervaiz A. Shah, Ikrima Khalid, Junaid Ahmad, Umar Farooq Gohar, Kok Khiang Peh, Muhammad Shahid Iqbal
Format: Article
Published: MDPI AG 2020-07-01
Online Access:https://www.mdpi.com/2073-4360/12/7/1564