Endogenous retroviral insertions drive non-canonical imprinting in extra-embryonic tissues

Endogenous retroviral insertions drive non-canonical imprinting in extra-embryonic tissues

Abstract Background Genomic imprinting is an epigenetic phenomenon that allows a subset of genes to be expressed mono-allelically based on the parent of origin and is typically regulated by differential DNA methylation inherited from gametes. Imprinting is pervasive in murine extra-embryonic lineage...

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Bibliographic Details
Main Authors: Courtney W. Hanna, Raquel Pérez-Palacios, Lenka Gahurova, Michael Schubert, Felix Krueger, Laura Biggins, Simon Andrews, Maria Colomé-Tatché, Deborah Bourc’his, Wendy Dean, Gavin Kelsey
Format: Article
Language:English
Published: BMC 2019-10-01
Series:Genome Biology
Subjects:
Genomic imprinting
Histone modifications
Extra-embryonic
Development
Embryo
H3K27me3
Online Access:http://link.springer.com/article/10.1186/s13059-019-1833-x

Internet

http://link.springer.com/article/10.1186/s13059-019-1833-x

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