Taxifolin is a rat and human 11β-hydroxysteroid dehydrogenase 1 inhibitor as a possible drug to treat the metabolic syndrome

Taxifolin is a rat and human 11β-hydroxysteroid dehydrogenase 1 inhibitor as a possible drug to treat the metabolic syndrome

11β-Hydroxysteroid dehydrogenase 1 (HSD11B1) is an NADPH-dependent oxidoreductase that elevates cortisol (in human beings) or corticosterone (in rats) locally via metabolically activating 11 keto-glucocorticoids. Taxifolin is a flavonoid in food plants. The present study investigated the effects of...

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Bibliographic Details
Main Authors: Jianliang Sun, Fei Ge, Yiyan Wang, Yaoyao Dong, Yuanyuan Shan, Qiqi Zhu, Xiaolong Wu, Chengyun Wu, Ren-Shan Ge
Format: Article
Language:English
Published: Elsevier 2018-10-01
Series:Journal of Functional Foods
Subjects:
Taxifolin
11β-hydroxysteroid dehydrogenase 1
Metabolic
Syndrome
Inhibitor
Corticosterone
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464618304432

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http://www.sciencedirect.com/science/article/pii/S1756464618304432

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