Taxifolin is a rat and human 11β-hydroxysteroid dehydrogenase 1 inhibitor as a possible drug to treat the metabolic syndrome
11β-Hydroxysteroid dehydrogenase 1 (HSD11B1) is an NADPH-dependent oxidoreductase that elevates cortisol (in human beings) or corticosterone (in rats) locally via metabolically activating 11 keto-glucocorticoids. Taxifolin is a flavonoid in food plants. The present study investigated the effects of...
Main Authors: | Jianliang Sun, Fei Ge, Yiyan Wang, Yaoyao Dong, Yuanyuan Shan, Qiqi Zhu, Xiaolong Wu, Chengyun Wu, Ren-Shan Ge |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2018-10-01
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Series: | Journal of Functional Foods |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1756464618304432 |
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