Metabolomics coupled with integrated approaches reveal the therapeutic effects of higenamine combined with [6]-gingerol on doxorubicin-induced chronic heart failure in rats

Metabolomics coupled with integrated approaches reveal the therapeutic effects of higenamine combined with [6]-gingerol on doxorubicin-induced chronic heart failure in rats

Abstract Background This study was aimed to investigate the therapeutic effects and potential mechanism of higenamine combined with [6]-gingerol (HG/[6]-GR) against doxorubicin (DOX)—induced chronic heart failure (CHF) in rats. Materials and methods Therapeutic effects of HG/[6]-GR on hemodynamics i...

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Bibliographic Details
Main Authors: Jianxia Wen, Xiao Ma, Ming Niu, Junjie Hao, Ying Huang, Ruilin Wang, Ruisheng Li, Jian Wang, Yanling Zhao
Format: Article
Language:English
Published: BMC 2020-11-01
Series:Chinese Medicine
Subjects:
Higenamine
[6]-gingerol
Metabolomics
Chronic heart failure
Energy metabolism
Molecular mechanisms
Online Access:http://link.springer.com/article/10.1186/s13020-020-00403-0

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http://link.springer.com/article/10.1186/s13020-020-00403-0

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