Baker’s Yeast Mediated Reduction of 2-Acetyl-3-methyl Sulfolane

The baker’s yeast mediated reduction of 2-acetyl-3-methyl sulfolane 1 to provide the corresponding alcohol 2 is described. Excellent efficiency and enantioselectivity (>98% ee) has been achieved under these mild environmentally benign reaction conditions. In direct contrast, the chemical redu...

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Bibliographic Details
Main Authors: Rebecca E. Deasy, Noreen O'Riordan, Anita R. Maguire
Format: Article
Language:English
Published: MDPI AG 2014-06-01
Series:Catalysts
Subjects:
Online Access:http://www.mdpi.com/2073-4344/4/2/186