Structure and mechanism of the Nap adhesion complex from the human pathogen Mycoplasma genitalium

The adhesion complex (Nap) in Mycoplasma genitalium is composed of the adhesin proteins P110 and P140 and essential for infectivity, motility and adhesion of this human pathogen. Here, the author present the structures of P140 alone and the P140/P110 complex in closed and open conformations and base...

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Bibliographic Details
Main Authors: David Aparicio, Margot P. Scheffer, Marina Marcos-Silva, David Vizarraga, Lasse Sprankel, Mercè Ratera, Miriam S. Weber, Anja Seybert, Sergi Torres-Puig, Luis Gonzalez-Gonzalez, Julian Reitz, Enrique Querol, Jaume Piñol, Oscar Q. Pich, Ignacio Fita, Achilleas S. Frangakis
Format: Article
Language:English
Published: Nature Publishing Group 2020-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-16511-2