Cryo-EM Reveals Architectural Diversity in Active Rotavirus Particles

Rotavirus is a well-studied RNA virus that causes severe gastroenteritis in children. During viral entry, the outer layer of the virion is shed, creating a double-layered particle (DLP) that is competent to perform viral transcription (i.e., mRNA synthesis) and launch infection. While inactive forms...

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Bibliographic Details
Main Authors: Mary Hauser, William J. Dearnaley, A. Cameron Varano, Michael Casasanta, Sarah M. McDonald, Deborah F. Kelly
Format: Article
Language:English
Published: Elsevier 2019-01-01
Series:Computational and Structural Biotechnology Journal
Online Access:http://www.sciencedirect.com/science/article/pii/S2001037019302259