Alkaloids Induce Programmed Cell Death in Bloodstream Forms of Trypanosomes (Trypanosoma b. brucei)

The potential induction of a programmed cell death (PCD) in Trypanosoma b. brucei by 55 alkaloids of the quinoline, quinolizidine, isoquinoline, indole, terpene, tropane, steroid, and piperidine type was studied by measuring DNA fragmentation and changes in mitochondrial membrane potential. For comp...

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Bibliographic Details
Main Authors: Michael Wink, Vera Rosenkranz
Format: Article
Language:English
Published: MDPI AG 2008-10-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/13/10/2462/