Elucidating the Interaction of CF Airway Epithelial Cells and Rhinovirus: Using the Host-Pathogen Relationship to Identify Future Therapeutic Strategies

Elucidating the Interaction of CF Airway Epithelial Cells and Rhinovirus: Using the Host-Pathogen Relationship to Identify Future Therapeutic Strategies

Chronic lung disease remains the primary cause of mortality in cystic fibrosis (CF). Growing evidence suggests respiratory viral infections are often more severe in CF compared to healthy peers and contributes to pulmonary exacerbations (PEx) and deterioration of lung function. Rhinovirus is the mos...

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Bibliographic Details
Main Authors: Kak-Ming Ling, Luke W. Garratt, Timo Lassmann, Stephen M. Stick, Anthony Kicic, WAERP, AusREC, Australian Respiratory Early Surveillance Team for Cystic Fibrosis
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-11-01
Series:Frontiers in Pharmacology
Subjects:
cystic fibrosis
airway epithelium
rhinovirus
innate immune response
therapy
transcriptomic
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2018.01270/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2018.01270/full

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