Cutaneous Squamous Cell Carcinoma Developing from Recessive Dystrophic Epidermolysis Bullosa: A Case Report and an Immunohistochemical Study

Cutaneous Squamous Cell Carcinoma Developing from Recessive Dystrophic Epidermolysis Bullosa: A Case Report and an Immunohistochemical Study

We describe a 49-year-old Japanese woman with cutaneous squamous cell carcinoma (SCC) developing from recessive dystrophic epidermolysis bullosa (RDEB). Interestingly, immunohistochemical staining revealed dense infiltration of CD163+ M2 macrophages and numerous Foxp3+ regulatory T cells (Tregs) aro...

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Bibliographic Details
Main Authors: Akira Tsukada, Taku Fujimura, Sadanori Furudate, Yumi Kambayashi, Yukikazu Numata, Takahiro Haga, Akira Hashimoto, Setsuya Aiba
Format: Article
Language:English
Published: Karger Publishers 2012-09-01
Series:Case Reports in Dermatology
Subjects:
Recessive dystrophic epidermolysis bullosa
Squamous cell carcinoma
Immunosuppressive cells
Carcinogenesis
Online Access:http://www.karger.com/Article/FullText/343082

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http://www.karger.com/Article/FullText/343082

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