An Antibody Specific for the Dog Leukocyte Antigen DR (DLA-DR) and Its Novel Methotrexate Conjugate Inhibit the Growth of Canine B Cell Lymphoma

An Antibody Specific for the Dog Leukocyte Antigen DR (DLA-DR) and Its Novel Methotrexate Conjugate Inhibit the Growth of Canine B Cell Lymphoma

Canine B-cell lymphoma (CBL) is an incurable, spontaneous lymphoid malignancy constituting an accurate animal model for testing novel therapeutic strategies in human medicine. Resources of available species-specific therapeutic monoclonal antibodies (mAbs) targeting CBL are scarce. The aim of the pr...

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Bibliographic Details
Main Authors: Marta Lisowska, Magdalena Milczarek, Jarosław Ciekot, Justyna Kutkowska, Wojciech Hildebrand, Andrzej Rapak, Arkadiusz Miazek
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:Cancers
Subjects:
passive immunotherapy
canine b-cell lymphoma
dla-dr
hla-dr
antibody-drug conjugate
adc
methotrexate
Online Access:https://www.mdpi.com/2072-6694/11/10/1438

Internet

https://www.mdpi.com/2072-6694/11/10/1438

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