Distinct and atypical intrinsic and extrinsic cell death pathways between photoreceptor cell types upon specific ablation of Ranbp2 in cone photoreceptors.

Non-autonomous cell-death is a cardinal feature of the disintegration of neural networks in neurodegenerative diseases, but the molecular bases of this process are poorly understood. The neural retina comprises a mosaic of rod and cone photoreceptors. Cone and rod photoreceptors degenerate upon rod-...

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Bibliographic Details
Main Authors: Kyoung-In Cho, Mdemdadul Haque, Jessica Wang, Minzhong Yu, Ying Hao, Sunny Qiu, Indulekha C L Pillai, Neal S Peachey, Paulo A Ferreira
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-06-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3688534?pdf=render