Generation of SARS-CoV-2 Spike Pseudotyped Virus for Viral Entry and Neutralization Assays: A 1-Week Protocol

Generation of SARS-CoV-2 Spike Pseudotyped Virus for Viral Entry and Neutralization Assays: A 1-Week Protocol

The COVID-19 pandemic caused by the SARS-CoV-2 coronavirus requires reliable assays for studying viral entry mechanisms which remains poorly understood. This knowledge is important for the development of therapeutic approaches to control SARS-CoV-2 infection by permitting the screening for neutraliz...

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Bibliographic Details
Main Authors: Jose Manuel Condor Capcha, Guerline Lambert, Derek M. Dykxhoorn, Alessandro G. Salerno, Joshua M. Hare, Michael A. Whitt, Savita Pahwa, Dushyantha T. Jayaweera, Lina A. Shehadeh
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
SARS-CoV-2
pseudovirus
lentivirus
ACE2
TMPRSS2
furin
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2020.618651/full

Internet

https://www.frontiersin.org/articles/10.3389/fcvm.2020.618651/full

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