Syk Kinase Inhibitors Synergize with Artemisinins by Enhancing Oxidative Stress in <i>Plasmodium Falciparum</i>-Parasitized Erythrocytes

Syk Kinase Inhibitors Synergize with Artemisinins by Enhancing Oxidative Stress in <i>Plasmodium Falciparum</i>-Parasitized Erythrocytes

Although artemisinin-based combination therapies (ACTs) treat <i>Plasmodium falciparum</i> malaria effectively throughout most of the world, the recent expansion of ACT-resistant strains in some countries of the Greater Mekong Subregion (GMS) further increased the interest in improving t...

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Bibliographic Details
Main Authors: Ioannis Tsamesidis, Karine Reybier, Giuseppe Marchetti, Maria Carmina Pau, Patrizia Virdis, Claudio Fozza, Francoise Nepveu, Philip S. Low, Francesco Michelangelo Turrini, Antonella Pantaleo
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Antioxidants
Subjects:
<i>Plasmodium falciparum</i>
syk kinase inhibitors
artemisinin derivatives
hemichromes
oxidative stress
reactive oxygen species
Online Access:https://www.mdpi.com/2076-3921/9/8/753

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https://www.mdpi.com/2076-3921/9/8/753

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